Our Mission and Why We Started ArrePath
ArrePath was founded upon the mission to discover new and differentiated classes of small molecule therapeutics through the application of state of the art technologies and novel strategies.
Pharma R&D is increasingly capital inefficient, with reduced novelty and risk tolerance, leaving certain therapeutic areas underserved and high unmet needs unaddressed.
ArrePath applies world-class science and innovation in imaging and AI / ML technologies to accelerate the discovery and development of novel drugs to address global health issues.
We have established early proof of concept with the discovery of several novel antibiotics and are now expanding our pipeline into additional disease within and outside infectious diseases.
ArrePath's Leadership Team
ArrePath brings together world-class scientists and experts in drug discovery, microbiology, microscopy, and data science with a shared goal to develop life-saving medicines.
Kevin Krause, M.B.A.
President and Chief Executive Officer
Kevin Krause, M.B.A.
President and Chief Executive Officer
Mr. Krause brings more than 25 years of experience in research, clinical development, commercialization, and corporate development in the biotech industry.
Mr. Krause most recently served as the Chief Strategy Officer of AN2 Therapeutics, Inc., a company applying boron chemistry to the discovery and development of novel therapies. In this role, he was the Project Team leader for AN2’s epetraborole Phase 2/3 NTM lung disease program, while overseeing various departments including Project Management, Clinical Operations, Regulatory, Quality, Medical Writing, and Corporate Development. Earlier in his career, he held various positions in R&D leadership and Corporate Business Development at Achaogen, Cerexa, and Theravance BioPharma where he was instrumental in the clinical development and/or approval of Zemdri® (plazomicin), Avycaz® (ceftazidime-avibactam), Vibativ® (telavancin), Teflaro® (ceftaroline fosamil), Colobreathe® (inhaled colistin) and Quinsair® (inhaled levofloxacin).
Mr. Krause received an M.B.A. from the University of California, Berkeley Haas School of Business and a B.S. in Cell and Molecular Biology from San Francisco State University.
Alita Miller, Ph. D.
Chief Scientific Officer
Alita Miller, Ph. D.
Chief Scientific Officer
Alita is an expert in antibacterial discovery and development with over 20 years of experience in the field. Prior to joining ArrePath, she was Senior Vice President of Biology at Entasis Therapeutics, a company dedicated to the discovery and development of novel antibacterial agents to treat serious infections by resistant Gram-negative bacteria. At Entasis, Alita oversaw both preclinical biology and developmental microbiology research and played a key role in the development of Xacduro, which was FDA-approved in 2023. Prior to Entasis, Alita was first at Pfizer where she led both large and small molecule antibacterial discovery projects and then at AstraZeneca, where she was Head of Microbial Genetics and Genomics. She has served on numerous NIAID review panels and Scientific Advisory Boards related to the field.
Alita obtained a BA in chemistry from Kalamazoo College and worked as a chemist at both Merck and Eli Lilly before obtaining a PhD in Biochemistry and Molecular Biology from the University of Chicago. Her postdoctoral training was in the DiRita lab at the University of Michigan characterizing the molecular drivers of pathogenesis in Streptococcus pyogenes.
Kurt Thorn, Ph. D.
Chief Technology Officer
Kurt Thorn, Ph. D.
Chief Technology Officer
Kurt is a leader in the field of imaging and data sciences and , prior to joining ArrePath, was Senior Director Data Science at Zymergen, where he oversaw the building of a wide variety of data science tools, including statistical models for analysis of high throughput screening and fermentation data, recommendation algorithms for protein sequences catalyzing desired enzymatic functions and prediction of beneficial genetic edits for strain engineering, and chemical machine learning for predicting molecular properties from chemical structures.
Prior to Zymergen, Kurt spent 11 years at UCSF as an adjunct professor and director of the Nikon Imaging Center at UCSF/QB3, a highly successful light microscopy core facility, with 300 annual users and 40 papers published per year. He also ran an NIH-funded research lab that focused development of an integrated microscopy and microfluidic platform to enable highly multiplexed biochemical assays.
Kurt earned a bachelor’s degree in chemistry from Princeton University and a PhD in biophysics from UCSF, where he studied kinesin motility using single molecule imaging. Following UCSF, he was a fellow at the Bauer Center for Genomic Research at Harvard University, where he developed in vivo FRET bioassays.
Board
Zemer Gitai, Ph. D.
Founder and Chair, SAB
Edwin Grant Conklin Professor of Biology, Professor of Molecular Biology, Princeton University
Zemer Gitai, Ph. D.
Founder and Chair, SAB
Edwin Grant Conklin Professor of Biology, Professor of Molecular Biology, Princeton University
Zemer is a leader in applying quantitative and computational approaches to bacterial cell biology and antibiotic development. He graduated with a bachelor’s degree from MIT in 1996, completed his graduate studies at UCSF in 2002, and joined the faculty of Princeton University in 2005 after completing a postdoc at Stanford University. At Princeton, Dr. Gitai was promoted to Associate Professor with tenure in 2012 and to Professor in 2015. In 2016 he became the Edwin Grant Conklin Distinguished Professor of Biology. He was also the Director of Graduate Studies for the Department of Molecular Biology from 2012-2018. Dr. Gitai’s achievements have been recognized by many prestigious awards, including the NIH Director’s Pioneer Award, the NIH New Innovator Award, the NIH Transformative Research Award, the Beckman Young Investigator Award, and the HFSP Young Investigator Award.
Kevin Krause, M.B.A.
President and Chief Executive Officer
Kevin Krause, M.B.A.
President and Chief Executive Officer
Mr. Krause brings more than 25 years of experience in research, clinical development, commercialization, and corporate development in the biotech industry.
Mr. Krause most recently served as the Chief Strategy Officer of AN2 Therapeutics, Inc., a company applying boron chemistry to the discovery and development of novel therapies. In this role, he was the Project Team leader for AN2’s epetraborole Phase 2/3 NTM lung disease program, while overseeing various departments including Project Management, Clinical Operations, Regulatory, Quality, Medical Writing, and Corporate Development. Earlier in his career, he held various positions in R&D leadership and Corporate Business Development at Achaogen, Cerexa, and Theravance BioPharma where he was instrumental in the clinical development and/or approval of Zemdri® (plazomicin), Avycaz® (ceftazidime-avibactam), Vibativ® (telavancin), Teflaro® (ceftaroline fosamil), Colobreathe® (inhaled colistin) and Quinsair® (inhaled levofloxacin).
Mr. Krause received an M.B.A. from the University of California, Berkeley Haas School of Business and a B.S. in Cell and Molecular Biology from San Francisco State University.
Dylan Morris
Managing Director, Insight Partners
Dylan Morris
Managing Director, Insight Partners
Dylan Morris is a Managing Director at Insight. He joined the firm in 2021 to focus on investments in computational biology. Dylan was previously a general partner at CRV, where he built the bioengineering practice, leading the firm’s investments in Dyno Therapeutics, Recursion Pharmaceuticals, and Plexium, among others. Prior to CRV, Dylan invested at Innovation Endeavors, Eric Schmidt’s early stage venture capital firm, where he drove investments in companies operating at the intersection of data science and life science.
Before becoming an investor, Dylan cofounded Integrated Plasmonics, a venture-backed point-of-care diagnostics startup. Prior to that, he conducted graduate research in biochemistry and molecular biophysics at Caltech, where he co-authored multiple peer-reviewed publications. Dylan received his A.B. in Computer Science from Harvard University.
Fei Shen, Ph. D.
Managing Director, Boehringer Ingelheim Venture Fund USA
Fei Shen, Ph. D.
Managing Director, Boehringer Ingelheim Venture Fund USA
Fei received her Ph.D. in Neuropharmacology from Loyola University Chicago Stritch School of Medicine and a B.Sc in Biochemistry from East China University Science & Technology. In 2007, she started her industrial career at Theravance Biopharma as an in vivo pharmacologist and led a lab in driving multiple research projects from exploratory, lead optimization to development candidate nomination, including TD-1473 in Ulcerative Colitis, Ampreloxetine in Fibromyalgia, Velusetrag in Gastroparesis, TD-8954 in Post-operative Gastrointestinal Dysfunction. In 2015, she joined Boehringer Ingelheim Pharmaceuticals Inc. Global Immunology and Respiratory Disease Research in Ridgefield where she started as a Laboratory Head and became the Head of in vivo Pharmacology group in 2016. From 2015 to 2020, before joining the BI Venture Fund, Fei led a group of ~20 in vivo pharmacologists supporting the Immunology and Respiratory Portfolio for small molecule, antisense and antibody projects.
Venkat Srinivasan, Ph. D.
Managing Director, Innospark Ventures
Venkat Srinivasan, Ph. D.
Managing Director, Innospark Ventures
Venkat Srinivasan is a serial entrepreneur and investor. Innospark Ventures is an evergreen venture fund investing in early stage AI led startups. He brings deep expertise in AI and computational algorithms to the firm, especially natural language understanding, combined with deep functional knowledge in multiple domains including operations research, finance and accounting. He has founded several successful AI-led startups, including eCredit, Corporate Fundamentals and Rage Frameworks. More recently he has founded EnglishHelper (using AI to solve illiteracy at scale), Gyan.AI (first explainable natural language understanding engine), Creda Health (Digital Health Assistant for continuum of care) and PrismX (automated software development platform).
Venkat was honored with a Lifetime Achievement Award by The Indus Entrepreneurs [TiE] in 2017 (http://bit.ly/2j5ElGG). Dr. Srinivasan holds 9 patents, has published over 30 research papers in prestigious peer-reviewed journals, has co-edited two books and is the author of a book titled, The Intelligent Enterprise in the Era of Big Data (Wiley, 2017). Venkat has strongly advocated for and believes that successful AI-led transformation will be characterized by explainability, traceability, context awareness and the ability to learn from sparse data environments.
Prior to his entrepreneurial career, Venkat served as an Associate Professor at the D’More-McKim School of Business at Northeastern University.